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Results for "

<i>Pyrola calliantha<_i> H. Andr.

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (1) 5 alpha Reductase (12) 5-HT Receptor (90) Acetolactate Synthase (ALS) (1) Acetyl-CoA Carboxylase (2) Ack1 (1) Acyltransferase (6) ADAMTS (2) ADC Antibody (3) ADC Cytotoxin (49) ADC Linker (41) Adenosine Deaminase (1) Adenosine Receptor (16) Adenylate Cyclase (6) Adrenergic Receptor (85) AIM2 (2) Akt (43) Aldehyde Dehydrogenase (ALDH) (2) Aldose Reductase (1) Amino Acid Decarboxylase (1) Amino Acid Derivatives (286) Aminopeptidase (22) Aminotransferases (Transaminases) (4) AMPK (16) Amylases (3) Amyloid-β (23) Anaplastic lymphoma kinase (ALK) (18) Androgen Receptor (15) Angiotensin Receptor (33) Angiotensin-converting Enzyme (ACE) (50) Annexin A (1) Antibiotic (155) Antibody-Drug Conjugates (ADCs) (13) Antifolate (2) AP-1 (4) Apelin Receptor (APJ) (1) Apolipoprotein (2) Apoptosis (493) Aquaporin (2) Arenavirus (7) Arginase (6) Arp2/3 Complex (1) Aryl Hydrocarbon Receptor (9) ASCT (1) ATF6 (1) Atg8/LC3 (4) ATM/ATR (10) ATP Synthase (2) ATTECs (1) Aurora Kinase (15) Autophagy (163) Bacterial (440) Bcl-2 Family (32) BCL6 (2) Bcr-Abl (28) BCRP (2) Beclin1 (3) Beta-lactamase (4) Beta-secretase (4) Biochemical Assay Reagents (358) Bombesin Receptor (2) Bradykinin Receptor (6) Btk (10) c-Fms (1) c-Kit (4) c-Met/HGFR (9) c-Myc (7) C-type Lectin-like Receptors (CTLRs) (1) Cadherin (1) Calcium Channel (62) Calmodulin (1) CaMK (7) Cannabinoid Receptor (11) Carbonic Anhydrase (83) Carboxylesterase (CES) (1) Casein Kinase (10) Caspase (37) CaSR (5) Cathepsin (11) CCR (8) CD19 (3) CD20 (2) CD276/B7-H3 (6) CD28 (1) CD3 (10) CD38 (2) CD47 (4) CDK (52) Ceramidase (1) CFTR (4) Checkpoint Kinase (Chk) (2) Chloride Channel (3) Cholecystokinin Receptor (13) Cholinesterase (ChE) (47) ClpP (1) CMV (3) Collagen (2) Complement System (6) Constitutive Androstane Receptor (1) COX (41) CRAC Channel (2) CRFR (7) Cuproptosis (2) CXCR (20) Cyclic GMP-AMP Synthase (5) Cyclin G-associated Kinase (GAK) (2) Cytochrome P450 (49) Dengue Virus (9) Deubiquitinase (14) DGK (2) 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(14) Fluorescent Dye (236) Folate Receptor (FR) (1) Formyl Peptide Receptor (FPR) (3) FOXO (3) Free Fatty Acid Receptor (3) Fungal (89) FXR (7) G protein-coupled Bile Acid Receptor 1 (1) G Protein-coupled Receptor Kinase (GRK) (2) G-quadruplex (2) GABA Receptor (29) GCGR (5) GGTase (6) GHSR (4) GLP Receptor (10) Glucocorticoid Receptor (2) Glucokinase (1) Glucosylceramide Synthase (GCS) (6) GLUT (6) Glutaminase (2) Glutathione Peroxidase (8) Glutathione S-transferase (2) Glycosidase (21) Glycosyltransferase (1) Glyoxalase (GLO) (11) GlyT (6) GnRH Receptor (3) GPR119 (1) GPR88 (1) GSK-3 (12) Guanylate Cyclase (2) Haspin Kinase (2) HBV (14) HCV (30) HCV Protease (5) HDAC (97) Hedgehog (3) Heme Oxygenase (HO) (3) Herbicide (9) HIF/HIF Prolyl-Hydroxylase (17) Hippo (MST) (1) Histamine Receptor (496) Histone Acetyltransferase (20) Histone Demethylase (62) Histone Methyltransferase (97) HIV (75) HIV Integrase (8) HIV Protease (5) HMG-CoA Reductase (HMGCR) (1) HPV (6) HSP (22) HSV (11) IAP (1) IFNAR (17) IGF-1R (10) iGluR (27) IKK (27) IKZF Family (2) Imidazoline Receptor (30) IMPDH (1) Indoleamine 2,3-Dioxygenase (IDO) (7) Influenza Virus (120) Insecticide (16) Insulin Receptor (9) Integrin (11) Interleukin Related (38) IRAK (8) IRE1 (2) Isocitrate Dehydrogenase (IDH) (31) Isotope-Labeled Compounds (319) Itk (4) JAK (30) JNK (17) Keap1-Nrf2 (17) Lactate Dehydrogenase (3) LAG-3 (2) LDLR (1) Leukotriene Receptor (18) Ligands for E3 Ligase (8) Ligands for Target Protein for PROTAC (7) LIM Kinase (LIMK) (1) Lipase (2) Liposome (10) Lipoxygenase (12) LOX-1 (2) LPL Receptor (9) LRRK2 (2) LXR (4) mAChR (33) Macrophage migration inhibitory factor (MIF) (1) MAGL (3) MAP3K (9) MAP4K (5) MAPKAPK2 (MK2) (2) MARCKS (1) Mas-related G-protein-coupled Receptor (MRGPR) (1) MDM-2/p53 (20) MEK (2) Melanocortin Receptor (8) Melatonin Receptor (1) Methionine Adenosyltransferase (MAT) (3) mGluR (25) MHC (23) MicroRNA (95) Microtubule/Tubulin (33) Mineralocorticoid Receptor (3) Mitochondrial Metabolism (43) Mitophagy (16) Mitosis (4) Mixed Lineage Kinase (4) MMP (38) Molecular Glues (6) Monoamine Oxidase (29) Monoamine Transporter (3) Monocarboxylate Transporter (1) Mps1 (2) mTOR (29) Mucin (1) MyD88 (1) Myosin (2) Na+/Ca2+ Exchanger (3) Na+/H+ Exchanger (NHE) (20) Na+/K+ ATPase (13) nAChR (13) NADPH Oxidase (2) NAMPT (4) Natriuretic Peptide Receptor (NPR) (2) Necroptosis (5) NEKs (1) Neprilysin (1) Neurokinin Receptor (17) Neuropeptide Y Receptor (5) Neurotensin Receptor (7) NF-κB (98) NKCC (1) NO Synthase (30) NOD-like Receptor (NLR) (10) Notch (4) NTPDase (7) Nuclear Hormone Receptor 4A/NR4A (2) Nucleoside Antimetabolite/Analog (149) Oct3/4 (2) Olfactory Receptor (1) Opioid Receptor (20) Orexin Receptor (OX Receptor) (1) Organoid (16) Orphan Receptor (1) Orthopoxvirus (3) Oxidative Phosphorylation (11) Oxytocin Receptor (1) P-glycoprotein (13) P2X Receptor (6) P2Y Receptor (1) p38 MAPK (29) p62 (2) p97 (2) PACAP Receptor (6) PAI-1 (3) PAK (2) Paraptosis (1) Parasite (91) PARP (31) PCSK9 (1) PD-1/PD-L1 (20) PDGFR (8) PDHK (1) PDK-1 (3) Penicillin-binding protein (PBP) (4) Peptide-Drug Conjugates (PDCs) (1) PERK (5) PGE synthase (9) Phosphatase (16) Phosphodiesterase (PDE) (28) Phosphoglycerate Dehydrogenase (PHGDH) (1) Phospholipase (12) Photosensitizer (2) Phytohormone (1) PI3K (56) PI4K (2) PI4P5K (1) Piezo Channel (2) Pim (6) PIN1 (1) PKA (30) PKC (28) PKD (2) PKG (8) Platelet-activating Factor Receptor (PAFR) (7) Polo-like Kinase (PLK) (8) Potassium Channel (61) PPAR (15) Prion Protein (2) Prolyl Endopeptidase (PREP) (2) Prostaglandin Receptor (43) PROTAC Linkers (26) PROTACs (112) Protease Activated Receptor (PAR) (5) Proteasome (30) Protein Arginine Deiminase (7) Protein Prenyltransferase (2) Proton Pump (101) Protoporphyrinogen IX oxidase (4) PSMA (6) PTEN (1) Pyroptosis (7) Pyruvate Kinase (3) Quinone Reductase (4) RAD51 (1) Radionuclide-Drug Conjugates (RDCs) (5) Raf (10) RAR/RXR (2) Ras (61) Reactive Oxygen Species (97) Reference Standards (64) Renin (4) RET (1) Reverse Transcriptase (6) RIP kinase (8) RNA MTase (1) ROCK (17) ROR (4) ROS Kinase (7) RSV (3) RXFP Receptor (3) Salt-inducible Kinase (SIK) (1) SARS-CoV (45) Scavenger Receptor Class B type I (SR-BI） (2) Ser/Thr Kinase (2) Ser/Thr Protease (19) Serotonin Transporter (7) SF3B1 (2) SGK (1) SGLT (5) SHMT (1) SHP2 (4) Sigma Receptor (9) Sirtuin (8) Small Interfering RNA (siRNA) (171) SNIPERs (1) SOD (7) Sodium Channel (41) Somatostatin Receptor (2) SOS1 (6) SphK (3) Src (13) STAT (28) Stearoyl-CoA Desaturase (SCD) (2) Steroid Sulfatase (1) STING (28) Succinate Dehydrogenase (1) Survivin (5) SWI/SNF Complex (2) Syk (1) TAM Receptor (5) Taste Receptor (1) Tau Protein (3) Telomerase (3) TGF-beta/Smad (13) TGF-β Receptor (43) Thrombin (7) Thymidylate Synthase (3) Tim3 (1) TMV (3) TNF Receptor (48) TNK1 (1) Toll-like Receptor (TLR) (22) TOPK (4) Topoisomerase (224) Trace Amine-associated Receptor (TAAR) (2) Transferrin Receptor (1) Transmembrane Glycoprotein (12) Transthyretin (TTR) (6) Trk Receptor (7) TROP2 (1) TRP Channel (19) TrxR (3) Tyrosinase (7) URAT1 (2) VD/VDR (5) VEGFR (35) Virus Protease (11) VSV (1) WDR5 (9) Wee1 (2) Wnt (20) Xanthine Oxidase (5) YAP (12) α-synuclein (3) β-catenin (16) β-glucuronidase (1) γ-secretase (3)
By Research Areas:	Cancer (2426) Cardiovascular Disease (369) Endocrinology (358) Infection (875) Inflammation/Immunology (1072) Metabolic Disease (485) Neurological Disease (795)
Click Chemistry:	ADC Synthesis (2) TCO (3) Labeling and Fluorescence Imaging (6) DBCO (2) PROTAC Synthesis (2) Azide (58) Tetrazine (1) Alkynes (33)
Oligonucleotides:	miRNA mimics (24) Nucleosides and their Analogs (110) miRNA antagomirs (22) Nucleoside Phosphoramidites (8) Flavoring Agents (1) Rat Pre-designed siRNA Sets (28) miRNA inhibitors (22) Phospholipids (3) mRNA (1) Antisense Oligonucleotides (4) Cholesterol (1) siRNAs (169) miRNA agomirs (22) Pegylated Lipids (1) MicroRNAs (90) Aptamers (5) Mouse Pre-designed siRNA Sets (28) Cationic Lipids (1) Human Pre-designed siRNA Sets (113)

6776

Inhibitors & Agonists

Screening Libraries

198

Fluorescent Dye

281

Biochemical Assay Reagents

835

Peptides

MCE Kits

124

Inhibitory Antibodies

927

Natural
Products

1250

Recombinant Proteins

401

Isotope-Labeled Compounds

359

Antibodies

Click Chemistry

395

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W008452

H-Tyr(3-I)-OH	Endogenous Metabolite	Metabolic Disease
H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite .

HY-W007615

H-Phe(4-I)-OH	Amino Acid Derivatives	Others
H-Phe(4-I)-OH is a phenylalanine derivative .

HY-W011472

H-D-Phe(4-I)-OH	Amino Acid Derivatives	Others
H-D-Phe(4-I)-OH is a phenylalanine derivative .

HY-W009284

H-DL-Phe(4-I)-OH	Amino Acid Derivatives	Others
H-DL-Phe(4-I)-OH is a phenylalanine derivative .

HY-P10951

(R)-Zadavotide guraxetan (R)-PSMA I&T; (R)-PNT-2002	PSMA	Cancer
Zadavotide guraxetan (PSMA I&T; PNT-2002) is a prostate-specific membrane antigen (PSMA) inhibitor. Zadavotide guraxetan has antitumor activity and can be used in prostate cancer-targeted research .

HY-W008452S

H-Tyr(3-I)-OH-13C6	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
H-Tyr(3-I)-OH- ¹³C₆ is the ¹³C-labeled H-Tyr(3-I)-OH. H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite[1][2].

HY-150685

Topo I/COX-2-IN-1	Topoisomerase Prostaglandin Receptor Apoptosis	Inflammation/Immunology Cancer
Topo I/COX-2-IN-1 (1H-30) is a potential Topo I/COX-2 inhibitor. Topo I/COX-2-IN-1 inhibits COX-2 and Topo I with the IC₅₀ value of 0.24 μM and 4.42 μM, respectively. Topo I/COX-2-IN-1 can induce apoptosis and inhibit migration of cancer cells, has anti-cancer activity .

HY-147986

hCA I-IN-2	Carbonic Anhydrase	Cancer
hCA I-IN-2 (Compound 6d) is a selective human carbonic anhydrase I (hCA I) inhibitor with K_i values of 18.8, 375.1, 1721 and 283.9 nM against hCA I, hCA II, hCAIX and hCAXII, respectively .

HY-147985

hCA I-IN-1	Carbonic Anhydrase	Cancer
hCA I-IN-1 (Compound 6q) is a human carbonic anhydrase I (hCA I) inhibitor with K_i values of 38.3, 716.4, 940.1 and 192.8 nM against hCA I, hCA II, hCAIX and hCAXII, respectively .

HY-156969

Topoisomerase I inhibitor 11	Topoisomerase Btk	Cancer
Topoisomerase I inhibitor 11 is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 11 can bind to BTK .

HY-162091

Topoisomerase I inhibitor 13	Topoisomerase	Cancer
Topoisomerase I inhibitor 13 (Compound G11) is a Topo I inhibitor that inhibits cancer cell proliferation. Topoisomerase I inhibitor 13 significantly inhibits tumor growth in vivo .

HY-122949

Momordicine I	DGK	Metabolic Disease
Momordicine I, a triterpenoid compound extracted from momordica charantia L. Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ .

HY-NP090A

Ulex Europaeus Agglutinin I (peroxidase) UEA I (peroxidase)	Biochemical Assay Reagents	Others
Ulex Europaeus Agglutinin I (peroxidase) (UEA I (peroxidase)) has anti-H blood group specificity. Ulex Europaeus Agglutinin I (peroxidase) has an affinity for L-fucose .

HY-N12370

Tenaxin I	Others	Others
Tenaxin I is a component extracted from Radix Scutellariae with neuraminidase inhibitory activity .

HY-146437

Topoisomerase I inhibitor 6	Topoisomerase	Cancer
Topoisomerase I inhibitor 6 (Compound 3) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 6 is able to trap DNA-Top1 cleavage complex and found to be less cytotoxic in non-cancerous cell line. Topoisomerase I inhibitor 6 has the potential for the research of cancer diseases .

HY-P1032F

Biotinyl-Angiotensin I (human, mouse, rat)	Endogenous Metabolite	Endocrinology
Biotinyl-Angiotensin I (human, mouse, rat) is biotin-labeled Angiotensin I . Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE) .

HY-149002

Topoisomerase I/II inhibitor 4	Topoisomerase Apoptosis	Cancer
Topoisomerase I/II inhibitor 4 (compound F16) is a potent topoisomerase I (Topo I) and II (Topo II) dual inhibitor. Topoisomerase I/II inhibitor 4 inhibits cell proliferation, invasion and migration and induces apoptosis. Topoisomerase I/II inhibitor 4 can be used for liver cancer research .

HY-N0890

Tubeimoside I 3 Publications Verification Tubeimoside-1; Lobatoside-H	HSP NF-κB p38 MAPK Akt Autophagy Interleukin Related VEGFR	Cardiovascular Disease Inflammation/Immunology Cancer
Tubeimoside I is an orally active HSPD1 inhibitor. Tubeimoside I inhibits NF-κB, MAPK, as well as regulates eNOS-VEGF. Tubeimoside I induces cytoprotective Autophagy via an Akt-mediated pathway. Tubeimoside I inhibits proinflammatory cytokine (IL-6 and IL-1β) production. Tubeimoside I exhibits anti-inflammatory activities. Tubeimoside I promotes angiogenesis and improves sepsis symptoms. Tubeimoside I is used in the research of inflammatory diseases, various cancers, sepsis and ischemic diseases .

HY-147647

Glyoxalase I inhibitor 5	Glyoxalase (GLO)	Cancer
Glyoxalase I inhibitor 5 (Compound 9h) is a glyoxalase I (Glo-I) inhibitor with an IC₅₀ of 1.28 μM. Glyoxalase I inhibitor 5 can be used as anticancer agent .

HY-P4569

H-Ser-Pro-OH	Dipeptidyl Peptidase	Others
H-Ser-Pro-OH is a dipeptide containing serine and proline, which can serve as a substrate for prolinase I (PD I) and PD II. H-Ser-Pro-OH can also be used for the synthesis of polypeptide .

HY-P0324

Parasin I	Bacterial	Infection
Parasin I is a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, and shows antimicrobial activity.

HY-146497

Topoisomerase I inhibitor 7	Topoisomerase	Cancer
Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lymphoma transplants. Topoisomerase I inhibitor 7 indicates prospects for further search of new antitumor agent candidates among the heteroarene-fused anthraquinones .

HY-128206

I3MT-3 5 Publications Verification HMPSNE	Hippo (MST)	Metabolic Disease
I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC₅₀=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes.?I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST .

HY-P3006

Des-Leu10-angiotensin I	Drug Metabolite	Cardiovascular Disease
Des-Leu10-angiotensin I is a nonapeptide that inhibits rabbit lung angiotensin-converting enzyme peptidyl-dipeptide hydrolase with a K_i value of 31 μM, which is generated from angiotensin I by the action of carboxypeptidase-like activities residing in the human platelet and mast cell .

HY-169628

Topoisomerase I/II inhibitor 7	Topoisomerase	Cancer
Topoisomerase I/II inhibitor 7 (Compound 5h) is a Topoisomerase I/II inhibitor .

HY-P10925A

I-67	β-catenin	Cancer
I-67, a structural isomer of I-66 (HY-P10925), is a potent β-catenin inhibitor with an IC₅₀ of <50 nM. I-67 can inhibits β-catenin and T-cell factor (TCF) transcription factor interaction. I-67 shows anticancer effects .

HY-P990195

Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8)	LAG-3	Others
Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse MHC Class I.

HY-153340

I-152	Keap1-Nrf2	Metabolic Disease
I-152 is a conjugate containing N-acetyl-cysteine (NAC) and cysteamine (MEA). I-152 activates NRF2 and ATF4 signals. I-152 has anti-proliferative properties .

HY-E70040

Endoglycoceramidase I (EGCase I)	Endogenous Metabolite	Metabolic Disease
Endoglycoceramidase I (EGCase I) is a glycosidase, is often used in biochemical studies. Endoglycoceramidase I catalyzes a transglycosylation reaction, which transfers the sugar moiety of GSLs to the primary hydroxyl group of several 1-alkanols .

HY-P10925

I-66	β-catenin	Cancer
I-66 is a potent β-catenin inhibitor with an IC₅₀ of <50 nM. I-66 can inhibits β-catenin and T-cell factor (TCF) transcription factor interaction. I-66 shows anticancer effects .

HY-143265

Topoisomerase I inhibitor 2	Topoisomerase Apoptosis Caspase	Cancer
Topoisomerase I inhibitor 2 (ZML-8) is a highly selective inhibitor of DNA topoisomerase I (Top1). Topoisomerase I inhibitor 2 inhibits Top1 activity and results DNA damage. Topoisomerase I inhibitor 2 blocks G2/M phase and induces apoptosis, exhibits anti-tumor effect .

HY-P5798

Fasciculin-I FAS-I	Cholinesterase (ChE)	Neurological Disease
Fasciculin-I is isolated from the mambas venom. Fasciculin-I exerts its toxic effects by inhibiting acetylcholinesterase (AChE). Fasciculin-I blocks α-neurotoxins of nicotinic acetylcholine receptors and cardiac toxins that interact with cell membranes .

HY-P2774

Glyoxalase I Glo-I	Biochemical Assay Reagents	Others
Glyoxalase I (Glo-I) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P0324A

Parasin I TFA	Bacterial	Infection
Parasin I (TFA) is a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, and shows antimicrobial activity .

HY-131577A

Neutral protease I Dispase I	Collagen	Others
Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin .

HY-P5179

Huwentoxin I HWTX-I	Calcium Channel Sodium Channel	Neurological Disease
Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels. Huwentoxin I inhibits sodium channels in rat hippocampus and cockroach dorsal unpaired median (DUM) neurons with IC₅₀ values of 66.1 and 4.80 nM, respectively .

HY-NP072

Maackia Amurensis Lectin I MAL I	Fluorescent Dye	Others
Maackia Amurensis Lectin I (MAL I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin I (MAL I) is a biological material or organic compound that can be used in life science research .

HY-NP079

Ricinus Communis Agglutinin I RCA I	Fluorescent Dye	Others
Ricinus Communis Agglutinin I (RCA I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) is a biological material or organic compound that can be used in life science research .

HY-NP090

Ulex Europaeus Agglutinin I UEA I	Fluorescent Dye	Others
Ulex Europaeus Agglutinin I (UEA I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) is a biological material or organic compound that can be used in life science research .

HY-N0890R

Tubeimoside I (Standard) Tubeimoside-1 (Standard); Lobatoside-H (Standard)	Apoptosis	Cancer
Tubeimoside I (Standard) is the analytical standard of Tubeimoside I. This product is intended for research and analytical applications. Tubeimoside I is an orally active HSPD1 inhibitor. Tubeimoside I inhibits NF-κB, MAPK, as well as regulates eNOS-VEGF. Tubeimoside I induces cytoprotective Autophagy via an Akt-mediated pathway. Tubeimoside I inhibits proinflammatory cytokine (IL-6 and IL-1β) production. Tubeimoside I exhibits anti-inflammatory activities. Tubeimoside I promotes angiogenesis and improves sepsis symptoms. Tubeimoside I is used in the research of inflammatory diseases, various cancers, sepsis and ischemic diseases .

HY-170912

Topo I/II-IN-2	Topoisomerase Apoptosis ROS Kinase Cytochrome P450 Caspase Bcl-2 Family PI3K Akt mTOR	Cancer
Topo I/II-IN-2 (Compound 3g) is an inhibitor of Topo I and Topo II. Topo I/II-IN-2 inhibits NCI-H446 cells and NCI-H1048 cells with IC₅₀s of 1.30 μM and 1.42 μM, respectively. Topo I/II-IN-2 induces mitochondrial Apoptosis, mitochondrial dysfunction and activity generation. Topo I/II-IN-2 inhibits the PI3K/Akt/mTOR pathway. Topo I/II-IN-2 prevents SCLC (small cell lung cancer) cell proliferation, invasion, and migration in vitro. .

HY-N12073

Monofucosyllacto-N-hexaose I MFLNH I	Others	Others
Monofucosyllacto-N-hexaose I (MFLNH I) is a composition of human milk oligosaccharide .

HY-136538

LQZ-7I	Survivin	Cancer
LQZ-7I is a survivin-targeting inhibitor. LQZ-7I inhibits survivin dimerization. LQZ-7I orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors .

HY-P3055

Dendrotoxin-I DTX-I	Potassium Channel	Neurological Disease Cancer
Dendrotoxin-I (DTX-I) is a potent K ⁺ channels blocker with IC₅₀s of 0.13-50 nM for voltage-gated potassium channel subunits K_V1.1, K_V1.2 and K_V1.6, respectively. Dendrotoxin-I, a neurotoxin, has the potential for cancer research .

HY-N11172

Schibitubin I	Others	Neurological Disease
Schibitubin I is a lignin. Schibitubin I has neuroprotective activity. Schibitubin I can be isolated from the fruits of Schisandra bicolor var. tuberculata .

HY-W035090

Chloro(trimethylphosphine)gold(I) (Trimethylphosphine)gold(I) chloride	Biochemical Assay Reagents Endogenous Metabolite
Chloro(trimethylphosphine)gold(I) ((Trimethylphosphine)gold(I) chloride) is a metal complex with antitumor activity. Chloro(trimethylphosphine)gold(I) has been studied as a potential chemotherapeutic compound in cancer inhibition. Chloro(trimethylphosphine)gold(I) can also be used in organic synthesis reactions as a catalyst to improve reaction efficiency. The biocompatibility of Chloro(trimethylphosphine)gold(I) makes it promising for application in medicine and materials science.

HY-E70280

Recombinant endoglycoceramidase I rEGCase I	Biochemical Assay Reagents	Metabolic Disease
Recombinant endoglycoceramidase I (rEGCase I) is a glycosidase that catalyzes the hydrolysis of the β-glycosidic linkage between oligosaccharides and ceramides. Recombinant endoglycoceramidase I catalyzes a transglycosylation reaction, which transfers the sugar moiety of glycosphingolipids (GSLs) to the primary hydroxyl group of several 1-alkanols .

HY-NP068

Griffonia (Bandeiraea) Simplicifolia Lectin I GSL I	Fluorescent Dye	Others
Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) is a biological material or organic compound that can be used in life science research .

HY-N12316

Goshuyuamide I	Others	Others
Goshuyuamide-I (compound 4) is a kind of alkaloid. Goshuyuamide-I can be isolated from the fruits of Euodia rutaecarpa. Goshuyuamide-I can be used in the research of analgesics .

HY-P3446A

Big Gastrin I (human) TFA	Cholecystokinin Receptor	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Big Gastrin I, human (TFA) is a gastrointestinal hormone consisting of 34 amino acids. Big Gastrin I, human (TFA) can be used as a potential substance for the study of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurological diseases or cardiovascular diseases .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W008452

H-Tyr(3-I)-OH	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite .

HY-122949

Momordicine I	Triterpenes Structural Classification Terpenoids Source classification Cucurbitaceae Plants Momordica charantia Linn.	DGK
Momordicine I, a triterpenoid compound extracted from momordica charantia L. Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ .

HY-N0890

Tubeimoside I 3 Publications Verification Tubeimoside-1; Lobatoside-H	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Cucurbitaceae Plants Bolbostemma paniculaum (Maxim)Franguet Disease Research Fields Cancer	HSP NF-κB p38 MAPK Akt Autophagy Interleukin Related VEGFR
Tubeimoside I is an orally active HSPD1 inhibitor. Tubeimoside I inhibits NF-κB, MAPK, as well as regulates eNOS-VEGF. Tubeimoside I induces cytoprotective Autophagy via an Akt-mediated pathway. Tubeimoside I inhibits proinflammatory cytokine (IL-6 and IL-1β) production. Tubeimoside I exhibits anti-inflammatory activities. Tubeimoside I promotes angiogenesis and improves sepsis symptoms. Tubeimoside I is used in the research of inflammatory diseases, various cancers, sepsis and ischemic diseases .

HY-P0324A

Parasin I TFA	Infection Structural Classification Natural Products Classification of Application Fields Animals Source classification Disease Research Fields	Bacterial
Parasin I (TFA) is a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, and shows antimicrobial activity .

HY-N12370

Tenaxin I	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Medicago truncatula Gaertn.	Others
Tenaxin I is a component extracted from Radix Scutellariae with neuraminidase inhibitory activity .

HY-P0324

Parasin I	Infection Natural Products Classification of Application Fields Animals Source classification Disease Research Fields	Bacterial
Parasin I is a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, and shows antimicrobial activity.

HY-N0890R

Tubeimoside I (Standard) Tubeimoside-1 (Standard); Lobatoside-H (Standard)	Triterpenes Structural Classification Terpenoids Source classification Cucurbitaceae Plants Bolbostemma paniculaum (Maxim)Franguet	Apoptosis
Tubeimoside I (Standard) is the analytical standard of Tubeimoside I. This product is intended for research and analytical applications. Tubeimoside I is an orally active HSPD1 inhibitor. Tubeimoside I inhibits NF-κB, MAPK, as well as regulates eNOS-VEGF. Tubeimoside I induces cytoprotective Autophagy via an Akt-mediated pathway. Tubeimoside I inhibits proinflammatory cytokine (IL-6 and IL-1β) production. Tubeimoside I exhibits anti-inflammatory activities. Tubeimoside I promotes angiogenesis and improves sepsis symptoms. Tubeimoside I is used in the research of inflammatory diseases, various cancers, sepsis and ischemic diseases .

HY-N12073

Monofucosyllacto-N-hexaose I MFLNH I	Structural Classification Polysaccharides Animals Source classification Saccharides	Others
Monofucosyllacto-N-hexaose I (MFLNH I) is a composition of human milk oligosaccharide .

HY-P3055

Dendrotoxin-I DTX-I	Structural Classification Animals Cyclopeptides Source classification Animal Venoms	Potassium Channel
Dendrotoxin-I (DTX-I) is a potent K ⁺ channels blocker with IC₅₀s of 0.13-50 nM for voltage-gated potassium channel subunits K_V1.1, K_V1.2 and K_V1.6, respectively. Dendrotoxin-I, a neurotoxin, has the potential for cancer research .

HY-N11172

Schibitubin I	Structural Classification Source classification Lignans Schisandra bicolor Cheng Phenylpropanoids Plants Schisandraceae	Others
Schibitubin I is a lignin. Schibitubin I has neuroprotective activity. Schibitubin I can be isolated from the fruits of Schisandra bicolor var. tuberculata .

HY-N12316

Goshuyuamide I	Structural Classification Alkaloids Source classification Evodia rutaecarpa (Juss.) Benth. Rutaceae Plants Indole Alkaloids	Others
Goshuyuamide-I (compound 4) is a kind of alkaloid. Goshuyuamide-I can be isolated from the fruits of Euodia rutaecarpa. Goshuyuamide-I can be used in the research of analgesics .

HY-N5196

Nocathiacin I Nocathiacine I	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Nocathiacin I (Nocathiacine I) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF) .

HY-107301

Dehydrosoyasaponin I Soyasaponin Be; DHS-I	Structural Classification Polysaccharides Leguminosae Source classification Plants Saccharides Medicago sativa L.	Potassium Channel
Dehydrosoyasaponin I (Soyasaponin Be;DHS-I), a triterpene glycoside, is a potent and reversible calcium-activated potassium (maxi-K) channels activator .

HY-N0407R

Picroside I (Standard)	Structural Classification Iridoids Terpenoids Source classification Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell	STAT
Picroside I (Standard) is the analytical standard of Picroside I. This product is intended for research and analytical applications. Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II . Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ .

HY-N1628

1β-Hydroxybaccatin I 1-Hydroxybaccatin I	Structural Classification Terpenoids Source classification Taxaceae Diterpenoids Plants Taxus wallichiana Zucc.	Others
1β-Hydroxybaccatin I (1-Hydroxybaccatin I) can be extracted from Taxus wallichiana .

HY-N11430

F1839-I	Structural Classification Monophenols Microorganisms Source classification Phenols	HIV
F1839-I is a compound that can be isolated from Stachybotrys. F1839-I has weak cytotoxicity and anti-HIV activity with an IC₅₀ value of 15.6 μM .

HY-N10076

Ganomycin I	Structural Classification Microorganisms Source classification Phenols Polyphenols	HMG-CoA Reductase (HMGCR) Glycosidase HIV Protease
Ganomycin I is a dual inhibitor of α-Glucosidase and HMG-CoA reductase. Ganomycin I can also inhibits HIV protease. Ganomycin I exhibits anti-diabetic and anti-osteoclastogenesis effects .

HY-N14084

Monamycin I	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Antibiotic Bacterial
Monamycin I is an ester peptide antibiotic. Monamycin I has activity against Gram-positive bacteria .

HY-N11455

Lacto-N-difucohexaose I LDFH I	Structural Classification Polysaccharides Microorganisms Source classification Saccharides	Others
Lacto-N-difucohexaose I (LNDFH I), a linker, could be used to combine oligosaccharides containing Lewis b sugar chain to water insoluble polysaccharide .

HY-N3340

Macrocarpal I	Structural Classification Terpenoids Sesquiterpenes Source classification Phenols Polyphenols Myrtaceae Plants Eucalyptus globulus Labill.	Fungal
Macrocarpal I is a phloroglucinol coupled sesquiterpenoid with antifungal activity. Macrocarpal I against C. glabrata with an IC₅₀ value of 0.75 μg/mL. Macrocarpal I can be isolated from the juvenile leaves of E. maideni .

HY-N7141R

Spiramycin I (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Anti-parasitic Disease Research	Antibiotic Parasite Bacterial
Spiramycin I (Standard) is the analytical standard of Spiramycin I. This product is intended for research and analytical applications. Spiramycin I is a macrolide antibiotic and antiparasitic .

HY-N15386

Hericenone I	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Drug Intermediate
Hericenone I (Compound 24) is an aromatic compound, which is found in Hericium erinaceum. Hericenone I can be biosynthetically generated from hericenone A via acid-catalyzed cyclization. Hericenone I is promising for research of neurodegenerative diseases .

HY-N8511

Acremine I	Structural Classification Natural Products Microorganisms Source classification	Fungal
Acremine I is a fungi inhibitor and also a metabolite of the endophytic fungus Acremonium byssoides. Acremine I can effectively inhibit Plasmopara viticola. Acremine I can be used for research on plant diseases, such as grape downy mildew .

HY-120860

Sporidesmolide I	Structural Classification Microorganisms Cyclopeptides Source classification	Others
Sporidesmolide I can be found in Sporidesmium bakeri. Sporidesmolide I is promising for research into diseases such as mammalian facial eczema .

HY-N8293

Eupalinolide I	Structural Classification Melilotus albus Desr. Terpenoids Sesquiterpenes Source classification Plants Compositae	Others
Eupalinolide I inhibits the viability of breast cancer cells. Eupalinolide I can be isolated from Eupatorium lindleyanum .

HY-B1411R

i-Inositol (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Source classification Disease markers Endocrine diseases Endogenous metabolite	Endogenous Metabolite
i-Inositol (Standard) is the analytical standard of i-Inositol. This product is intended for research and analytical applications. i-Inositol (myo-Inositol) is a compound of sugar alcohols. i-Inositol is involved in a series of biological processes such as insulin signal transduction and cytoskeletal transduction. i-Inositol mainly exists in glial cells and plays an osmotic role .

HY-N0612R

Siamenoside I (Standard)	Triterpenes Structural Classification Terpenoids Source classification Cucurbitaceae Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants	Others
Siamenoside I (Standard) is the analytical standard of Siamenoside I. This product is intended for research and analytical applications. Siamenoside I is one of the mogrosides that has several kinds of bioactivities.

HY-N0331

Ziyuglycoside I	Triterpenes Structural Classification Classification of Application Fields Sanguisorba officinalis Linn. Terpenoids Source classification Rosaceae Plants Disease Research Fields Cancer	MDM-2/p53 Apoptosis
Ziyuglycoside I isolated from S. officinalis root, has anti-wrinkle activity, and increases the expression of type I collagen. Ziyuglycoside I could be used as an active ingredient for cosmetics . Ziyuglycoside I triggers cell cycle arrest and apoptosis mediated by p53, it can be a potential agent candidate for treating triple-negative breast cancer (TNBC) .

HY-N12127

Gymnoside I	Orchidaceae Gymnadenia conopsea (L.) R. Br. Source classification Plants	Others
Gymnoside I (compound 1) is a glycosidoxybenzyl 2-isobutylmalic acid. Gymnoside I shows antiallergic activity in passive cutaneous allergic reaction (PCA) in mice. Gymnoside I can be used in research to treat asthma, neurasthenia and chronic hepatitis .

HY-N2541

Gymnemic acid I	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Asclepiadaceae Metabolic Disease Plants Disease Research Fields Gymnema sylvestre (Retz.) Schult.	Taste Receptor mTOR Autophagy Apoptosis
Gymnemic acid I is a bioactive triterpene saponin found in Gymnema sylvestre. Gymnemic acid I is an antisweetness inhibitor via human sweet receptor type 1 receptor 2 (T1R2) and T1R3. Gymnemic acid I is a ribosomal protein biosynthesis inhibitor. Gymnemic acid I has antidiabetic effects. Gymnema acid I induces autophagy-protected MIN-6 cells from apoptosis under high glucose stress by inhibiting the phosphorylation activity of mTOR .

HY-N8614

Peucedanocoumarin I	Structural Classification Natural Products Chrysanthemum × morifolium (Ramat.) Hemsl. Source classification Plants Umbelliferae	Others
Peucedanocoumarin I (compound 1) is a kind of dihydropyranocoumarin. Peucedanocoumarin I can be isolated from the root of f Peucedanum praeruptorum .

HY-N12718

Campneoside I	Structural Classification Source classification Phenols Polyphenols Bignoniaceae Plants Incarvillea compacta Maxim.	Others
Campneoside I is a bitter phenyl propanoid glycoside. Campneoside I can be isolated from the roots of Incarvillea compacta .

HY-N7218

Lysolipin I	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Lysolipin I is a lipophilic antibiotic from Streptomyces violaceoniger. Lysolipin I is active against Gram-positive and Gramnegative bacteria .

HY-N0331R

Ziyuglycoside I (Standard)	Triterpenes Structural Classification Sanguisorba officinalis Linn. Terpenoids Source classification Rosaceae Plants	MDM-2/p53 Apoptosis
Ziyuglycoside I (Standard) is the analytical standard of Ziyuglycoside I. This product is intended for research and analytical applications. Ziyuglycoside I isolated from S. officinalis root, has anti-wrinkle activity, and increases the expression of type I collagen. Ziyuglycoside I could be used as an active ingredient for cosmetics . Ziyuglycoside I triggers cell cycle arrest and apoptosis mediated by p53, it can be a potential agent candidate for treating triple-negative breast cancer (TNBC) .

HY-W019806

Lacto-N-fucopentaose I LNFP I	Infection Structural Classification Natural Products Polysaccharides Classification of Application Fields Animals Inflammation/Immunology Disease Research Fields Saccharides	Endogenous Metabolite CDK Reactive Oxygen Species Apoptosis Enterovirus Bacterial
Lacto-N-fucopentaose I (LNFPI) is a human milk oligosaccharide (HMO), possessing antiviral and antibacterial activity. Lacto-N-fucopentaose I can reduce capsid protein VP1 to block virus adsorption, promote CDK2 and reduce cyclin E to recover cell cycle S phase block. Lacto-N-fucopentaose I inhibits ROS production and apoptosis in virus-infected cells. Lacto-N-fucopentaose I can also regulate intestinal microbiota to affect immune system development .

HY-N15368

Pradimicinone I	Quinones Structural Classification Microorganisms Anthraquinones Source classification	Antibiotic Bacterial
Pradimicinone I (Compound 10), a Pradimicin A (HY-132191) analog, is an antibiotic. Pradimicinone I is promising for research of antibacterial agents .

HY-N0432R

Astragaloside I (Standard)	Triterpenes Structural Classification other families Leguminosae Terpenoids Source classification Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Plants	Wnt β-catenin
Astragaloside I (Standard) is the analytical standard of Astragaloside I. This product is intended for research and analytical applications. Astragaloside I, one of the main active ingredients in Astragalus membranaceus, has osteogenic properties. Astragaloside I stimulates osteoblast differentiation through the Wnt/β-catenin signaling pathway .

HY-N7022R

Eclalbasaponin I (Standard)	Triterpenes Structural Classification other families Terpenoids Source classification Plants	Others
Eclalbasaponin I (Standard) is the analytical standard of Eclalbasaponin I. This product is intended for research and analytical applications. Eclalbasaponin I is isolated from Eclipta prostrata L with antitumor activity. Eclalbasaponin I inhibits the proliferation of hepatoma cell smmc-7721 with an IC₅₀ value of 111.1703 μg/ml .

HY-122530

Juvocimene I	Structural Classification Natural Products Labiatae Source classification Plants Helenium arizonicum S.F.Blake	Insecticide
Juvocimene I is a potent juvenile hormone mimic. Juvocimene I can be isolated from the essential oil of sweet basil,Ocimum basilicum L .

HY-N2013

Aristolactam I 1 Publications Verification Aristololactam; Aristolactam	Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Inflammation/Immunology Disease Research Fields	Drug Metabolite Aquaporin Cadherin TGF-beta/Smad
Aristolactam I is an AQP1 inhibitor and Aristolochic acid I metabolite. Aristolactam I can be isolated from Aristolochia plants. Aristolactam I downregulates Twist1 expression, increases E-cadherin expression, and activates the TGF-β/Smad signaling pathway. Aristolactam I has anticancer activity against breast cancer. Aristolactam I is nephrotoxic. Aristolactam I is mainly used in the study of breast cancer and kidney diseases such as renal interstitial fibrosis .

HY-N0360R

Dihydrotanshinone I (Standard)	Quinones Structural Classification Labiatae Samanea saman (Jacq.) Merr. Source classification Plants Phenanthrenequinones	SARS-CoV
Dihydrotanshinone I (Standard) is the analytical standard of Dihydrotanshinone I. This product is intended for research and analytical applications. Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases. Dihydrotanshinone I exhibits entry-blocking effect for MERS-CoV.

HY-126476

Justicisaponin I	Justicia rotundifolia Nees Triterpenes Structural Classification Acanthaceae Terpenoids Source classification Plants	Others
Justicisaponin I can be used as an anti-fertility agent. Justicisaponin I stabilizes the acrosome membrane of sperm, and inhibits the release of acid hydrolase and sperm proteins .

HY-N15545

Thaigranatumin I	Structural Classification Natural Products Xylocarpus granatum J. Koenig Source classification Plants Meliaceae	Drug Derivative
Thaigranatumin I is a limonoid compound found in the seeds of the Thai mangrove (Xylocarpus granatum). Thaigranatumin I is promising for research of neurodegenerative diseases such as Parkinson's diseases .

HY-N1939R

Icariside I (Standard)	Flavonols Structural Classification Monophenols Flavonoids Source classification Phenols Epimedium brevicornu Maxim. Plants Berberidaceae	Others
Icariside I (Standard) is the analytical standard of Icariside I. This product is intended for research and analytical applications. Icariside I is a metabolite of Icarlin, which could regulate bone remodeling and is recognized as an effective agent for the treatment of osteoporosis.

HY-N8355

Beauveriolide I	Infection Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Disease Research Fields	Endogenous Metabolite
Beauveriolide I is the metabolite of Entomopathogenic Fungi Beauveria sp.. Beauveriolide I (1) exhibits moderate insecticidal activities against Spodoptera litura and Callosobruchus chinensis .

HY-N0047R

Polyphyllin I (Standard)	Structural Classification Liliaceae Paris polyphylla Smith Plants Saccharides Steroids	JNK mTOR Akt PDK-1 Autophagy Apoptosis
Polyphyllin I (Standard) is the analytical standard of Polyphyllin I. This product is intended for research and analytical applications. Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis .

HY-N7052

Tubulysin I	Structural Classification Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Disease Research Fields Cancer	ADC Cytotoxin Microtubule/Tubulin
Tubulysin I is a highly cytotoxic anti-microtubule toxin (anti-microtubule toxins) that is synthesized as an ADC cytotoxin (ADC Cytotoxin). Tubulysin I can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin I displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC₅₀ values in the low nanomolar range. Tubulysin I inhibits microtubule/tubulin polymerization and leads to cell cycle arrest and apoptosis .

HY-N1985

Acetylastragaloside I	Structural Classification Natural Products Leguminosae Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Plants	Parasite
Acetylastragaloside I is a glycoside that can be isolated from the roots of Astragalus baibutensis. Acetylastragaloside I is the first cycloartane-type triterpene with remarkable trypanocidal activity with IC₅₀ values of 9.5 and 5.0 μg/mL for *T. brucei rhodesiense* and *T. cruzi*, respectively. Acetylastragaloside I can be used for the research of trypanosome infection .

HY-N0407

Picroside I 6'-Cinnamoylcatalpol	Structural Classification Iridoids Classification of Application Fields Terpenoids Source classification Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell Inflammation/Immunology Disease Research Fields	STAT
Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II . Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ .

HY-N1939

Icariside I Icarisid I	Flavonols Structural Classification Monophenols Flavonoids Classification of Application Fields Source classification Other Diseases Phenols Epimedium brevicornu Maxim. Plants Berberidaceae Disease Research Fields	Others
Icariside I is a metabolite of Icarlin, which could regulate bone remodeling and is recognized as an effective agent for the treatment of osteoporosis.

Cat. No.	Product Name	Chemical Structure

HY-W653982

Coproporphyrin I-15N4
Coproporphyrin I- ¹⁵N₄ is a ¹⁵N-labeled Coproporphyrin I (HY-113318). Coproporphyrin I is an endogenous metabolite present in urine and blood that can be used for the research of liver disease and porphyria .

HY-143623S

Neo Spiramycin I-d3
Neo Spiramycin I-d₃ is the deuterium labeled Neo Spiramycin I (HY-143623) . Neo Spiramycin I (NSPI) is the active metabolite of Spiramycin (SPI) with antimicrobial activity. Neo Spiramycin is widely used in veterinary medicine .

HY-W019776

Sudan I-d5
Sudan I-d₅ is a the deuterated Sudan I. Sudan I is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus[1].

HY-P1032S2

Angiotensin I-13C6,15N (human, mouse, rat) TFA
Angiotensin I-13C6,15N (human, mouse, rat) TFA is ¹³C and ¹⁵N labeled Angiotensin I (human, mouse, rat) TFA. Angiotensin I-13C6,15N (human, mouse, rat) TFA is a precursor of angiotensin II and is cleaved into angiotensin II by angiotensin converting enzyme (ACE) .

HY-B1411S1

i-Inositol-d1
i-Inositol-d is the deuterium labeled i-Inositol .

HY-B1411S

i-Inositol-d6
i-Inositol-d₆ is the deuterium labeled i-Inositol. i-Inositol is a chemical compound, associated lipids are found in many foods, in particular fruit, especially cantaloupe and oranges.

HY-W008452S

H-Tyr(3-I)-OH-13C6
H-Tyr(3-I)-OH- ¹³C₆ is the ¹³C-labeled H-Tyr(3-I)-OH. H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite[1][2].

HY-W890109S

Spiramycin I-d3-1
Spiramycin I-d₃-1 is deuterium-labeled Spiramycin I .

HY-124211S

Dibenzo(a,i)pyrene-d14
Dibenzo(a,i)pyrene-d₁₄ is the deuterium labeled Dibenzo(a,i)pyrene .

HY-B0175S

Toltrazuril-d3
Toltrazuril-d₃ is deuterated labeled Toltrazuril. Toltrazuril (BAY-i 9142) is an antiprotozoal agent that acts upon Coccidia parasites.

HY-P1032S

Angiotensin I-13C19,15N3 (human, mouse, rat)

Angiotensin I- ¹³C₁₉, ¹⁵N₃ (human, mouse, rat) is the ¹³C and ¹⁵N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .

HY-W249514

1-Methyl-1H-pyrazole-4-boronic acid pinacol ester-d3
1-Methyl-1H-pyrazole-4-boronic acid pinacol ester-d₃ is the deuterium labeled 1-Methyl-1H-pyrazole-4-boronic acid pinacol ester (HY-I0308). 1-Methyl-1H-pyrazole-4-boronic acid pinacol ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W010452S1

3-Hydroxybutyric acid-13C4 sodium
3-Hydroxybutyric acid- ¹³C₄ (sodium) is the ¹³C labeled 3-Hydroxybutyric acid sodium (HY-W010452). 3-Hydroxybutyric acid sodium is a metabolite that is elevated in type I diabetes, and can modulate the properties of membrane lipids[1].

HY-W010452S2

3-Hydroxybutyric acid-13C2 sodium
3-Hydroxybutyric acid- ¹³C₂ (sodium) is the ¹³C labeled 3-Hydroxybutyric acid sodium (HY-W010452). 3-Hydroxybutyric acid sodium is a metabolite that is elevated in type I diabetes, and can modulate the properties of membrane lipids[1].

HY-18600AS

Azimilide-d8 dihydrochloride
Azimilide-d₈ (dihydrochloride) is the deuterium labeled Azimilide dihydrochloride. Azimilide Dihydrochloride (NE-10064 Dihydrochloride) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.

HY-16562S1

Irinotecan-d10 hydrochloride
Irinotecan-d₁₀ (hydrochloride) is the deuterium labeled Irinotecan. Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex .

HY-16562S

Irinotecan-d10
Irinotecan-d₁₀ is a deuterium labeled Irinotecan ((+)-Irinotecan). Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex .

HY-B0374S1

Moxonidine-d7
Moxonidine-d₇ is deuterated labeled Moxonidine (HY-B0374). Moxonidine (BDF5895) is an imidazoline type 1 receptor (I1-R) selective agonist and antihypertensive agent.

HY-B0374S2

Moxonidine-d3
Moxonidine-d₃ (BDF5895-d₃) is deuterium labeled Moxonidine. Moxonidine (BDF5895) is an imidazoline type 1 receptor (I1-R) selective agonist and antihypertensive agent.

HY-W008820S

Glutaric acid-d6 1 Publications Verification
Glutaric acid-d₆ is the deuterium labeled Glutaric acid. Glutaric acid is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I[1][2][3].

HY-B0374AS

Moxonidine-13C,d3 hydrochloride
Moxonidine- ¹³C,d₃ hydrochloride is ¹³C and deuterated labeled Moxonidine hydrochloride (HY-B0374A). Moxonidine (BDF5895) hydrochloride is an imidazoline type 1 receptor (I1-R) selective agonist and antihypertensive agent.

HY-W008820S1

Glutaric acid-d4
Glutaric acid-d₄ is the deuterium labeled Glutaric acid. Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I[1][2][3].

HY-W008820S2

Glutaric acid-d2
Glutaric acid-d₂ is the deuterium labeled Glutaric acid. Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I[1][2][3].

HY-154741S

6-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione-15N2
6-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione- ¹⁵N₂ is ¹⁵N labeled (HY-154741).

HY-W008385S

H-HoArg-OH-d4
H-HoArg-OH-d₄ is a deuterium labeled H-HoArg-OH (HY-W008385). H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.

HY-150678S

Adenosine:H20-13c
Adenosine:H20- ¹³C is the ¹³C labeled Adenosine:H20 .

HY-W010589S2

H-Abu-OH-d6
H-Abu-OH-d₆ is the deuterium labeled H-Abu-OH. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.

HY-W010589S

H-Abu-OH-d3
H-Abu-OH-d₃ is the deuterium labeled H-Abu-OH. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.

HY-W010589S1

H-Abu-OH-d2
H-Abu-OH-d₂ is the deuterium labeled H-Abu-OH. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.

HY-W012908S2

H-DL-Pro-OH-d3
H-DL-Pro-OH-d₃ is the deuterium labeled H-DL-Pro-OH.

HY-W007750S

H-Lys(Z)-OH-d3
H-Lys(Z)-OH-d₃ is the deuterium labeled H-Lys(Z)-OH.

HY-143907S

Atorvastatin EP impurity H-d5
Atorvastatin EP impurity H-d₅ is the deuterium labeled Atorvastatin EP impurity H .

HY-160219S

BTK-IN-33
BTK-IN-33 is a Btk inhibitor with anticancer effects (WO2023174300A1; compound I) .

HY-W010590S1

H-DL-Abu-OH-d6
H-DL-Abu-OH-d₆ is the deuterium labeled H-DL-Abu-OH[1].

HY-W018710S

2(3H)-Benzothiazolone-d4
2(3H)-Benzothiazolone-d₄ is the deuterium labeled 2(3H)-Benzothiazolone[1].

HY-W012908S

H-DL-Pro-OH-d7
H-DL-Pro-OH-d₇ is the deuterium labeled H-DL-Pro-OH (HY-W012908). H-DL-Pro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W007497S

H-β-Ala-NH2.-d4HCl
H-β-Ala-NH2.-d₄ HCl is the deuterium labeled H-β-Ala-NH2.HCl[1].

HY-I1111S

Fmoc-L-Val-OH-d8
Fmoc-L-Val-OH-d₈ is a deuterium labeled Fmoc-L-Val-OH (HY-I1111). Fmoc-L-Val-OH is a kind of protect amino acids . Fmoc-L-Val-OH-1- ¹³C 是一种 ¹³C 标记的 Fmoc-L-Val-OH (HY-I1111)。 Fmoc-L-Val-OH 是一种缬氨酸衍生物。

HY-W029450S

Tetrahydropyrimidine-2(1H)-thione-d6
Tetrahydropyrimidine-2(1H)-thione-d₆ is the deuterium labeled Tetrahydropyrimidine-2(1H)-thione[1].

HY-160220S

KRAS inhibitor-23
KRAS inhibitor-23 (Isomer 2 of compound i) is a potent inhibitor of KRAS that plays an important role in cancer research .

HY-W014340S

2-Nitro-9H-fluorene-d9
2-Nitro-9H-fluorene-d₉ is the deuterium labeled 2-Nitro-9H-fluorene[1].

HY-W101495S3

Boc-Leu-OH·H2O-d7
Boc-Leu-OH·H2O-d₇ is the deuterium labeled Boc-Leu-OH·H2O.

HY-W012997S

Tetrahydro-2H-pyran-2-one-d4
Tetrahydro-2H-pyran-2-one-d₄ is the deuterium labeled Tetrahydro-2H-pyran-2-one. Tetrahydro-2H-pyran-2-one is an endogenous metabolite with antioxidant capacity. Tetrahydro-2H-pyran-2-one is the small active molecule and can be used as drug intermediate .

HY-W101495S2

Boc-Leu-OH·H2O-d10
Boc-Leu-OH·H2O-d₁₀ is the deuterium labeled Boc-Leu-OH·H2O[1].

HY-W101495S1

Boc-Leu-OH·H2O-d3
Boc-Leu-OH·H2O-d₃ is the deuterium labeled Boc-Leu-OH·H2O[1].

HY-13566AS

Belotecan-d7 hydrochloride
Belotecan-d₇ (hydrochloride) is the deuterium labeled Belotecan hydrochloride. Belotecan hydrochloride (CKD-602 hydrochloride), a Topoisomerase I inhibitor, is a synthetic camptothecin derivative .

HY-W015224S

Methyl 2-(1H-indol-3-yl)acetate-d5
Methyl 2-(1H-indol-3-yl)acetate-d₅ is the deuterium labeled Methyl 2-(1H-indol-3-yl)acetate. Methyl 2-(1H-indol-3-yl)acetate is an endogenous metabolite.

HY-13768S1

Topotecan-d6
Topotecan-d₆ is the deuterium labeled Topotecan. Topotecan (SKF 104864A; NSC 609669) is a Topoisomerase I inhibitor. The IC₅₀ values of Topotecan at 24 h are 2.73±0.25 μM of U251 cells, 2.95±0.23 μM of U87 cells, 5.46±0.41 μM of GSCs-U251 and 5.95 μM of GSCs-U87 .

HY-69188S

3,4-Dihydro-2H-benzo[b][1,4]thiazine-d2
3,4-Dihydro-2H-benzo[b][1,4]thiazine-d₂ (3,4-Dihydro-2H-1,4-benzothiazine-d₂) is the deuterium labeled 3,4-Dihydro-2H-benzo[b][1,4]thiazine.

HY-W004264S

Tetrahydro-2H-pyran-4-ol-d5
Tetrahydro-2H-pyran-4-ol-d₅ is the deuterium labeled Tetrahydro-2H-pyran-4-ol[1].

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